GI Tract

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Esophagus

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Stomach

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Ileum

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Duodenum

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Jejunum

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Cecum

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Colon

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Portal Vein

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

GallBladder

Conventional

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF

Germ-free

THF 10-f-THF 5-10 Methylene THF 5-methyl-THF Folinic Acid Folic acid DHF 5-m-DHF