Chaudhari Lab's approach to microbiome research involves finding links between bacteria and diseases, testing how changing the microbiome affects health, and using advanced techniques to understand the role of bacteria in health and disease. This research could lead to new ways to treat or prevent diseases by targeting the microbiome.

Considered a new organ system in the body, the gut microbiome has specific biochemical interactions with other organs, directly affecting host physiology. Metabolites produced by gut bacteria represent one of the most dominant ways the microbiome interacts with the host. The Chaudhari Lab is interested in deciphering the unique gut metabolome and studying the biological functions of these metabolites in influencing health and disease.